ZOMETA^® effectively inhibits the vicious cycle of bone destruction in patients like Dieter when given 4 mg every 3 to 4 weeks^10,11

Bone resorption marker decreases rapidly following administration of ZOMETA on day 1¹¹
The effect of ZOMETA on bone resorption marker lessens after 3 to 4 weeks¹¹

Change from baseline in bone resorption marker^*
(after single 4-mg dose of ZOMETA; N=12)¹¹

Change from baseline in bone resorption marker after single 4-mg dose of ZOMETA graph

*Urinary N-telopeptide/creatinine ratio was chosen as the surrogate marker.

Only dosing every 3 to 4 weeks has been proven effective in reducing
or delaying SREs^2,12-14

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Disclaimer: This is an international website for ZOMETA^® (zoledronic acid) and is intended for healthcare professionals outside the US. If you are a US resident, please click on the US Residents link at the top of this page. The information on this site is not country-specific and may contain information that is outside the approved indications in the country in which you are located.

ZOMETA® effectively inhibits the vicious cycle of bone destruction in patients like Dieter when given 4 mg every 3 to 4 weeks10,11

Only dosing every 3 to 4 weeks has been proven effective in reducingor delaying SREs2,12-14

ZOMETA^® effectively inhibits the vicious cycle of bone destruction in patients like Dieter when given 4 mg every 3 to 4 weeks^10,11

Only dosing every 3 to 4 weeks has been proven effective in reducing
or delaying SREs^2,12-14