ZOMETA® Patient Case Study – Inhibits Vicious Cycle of Bone Destruction in Breast Cancer Patients
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ZOMETA is the current standard of care for the prevention of skeletal-related events (SREs)

Marta N.
  • Aged 57 years
  • Math teacher
  • Grandmother of 2
The Clinical Question
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ZOMETA® effectively inhibits the vicious cycle of bone destruction in patients like Marta when given 4 mg every 3 to 4 weeks10,12

  • Bone resorption marker decreases rapidly following administration of ZOMETA on day 112
  • The effect of ZOMETA on bone resorption marker lessens after 3 to 4 weeks12


Change from baseline in bone resorption marker*
(after single 4-mg dose of ZOMETA; N=12)12
*Urinary N-telopeptide/creatinine ratio was chosen as the surrogate marker.


Only dosing every 3 to 4 weeks has been proven effective in reducing
or delaying SREs4,7,13,14





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