ZOMETA® Dosing For Tumour-Induced Hypercalcaemia (TIH): Ensuring Renal Safety
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ZOMETA dosing and administration for TIH ZOMETA is the current standard of care for the prevention of skeletal-related events (SREs)


4mg dosing hydration strategies ensuring renal safety references

Assess renal function prior to treatment in patients with TIH

  • The risks and benefits of therapy should be evaluated in patients with TIH who have severe renal impairment1
  • No dose adjustment is necessary in patients with serum creatinine <400 μmol/L or <4.5 mg/dL1
    • — Patients with higher serum creatinine levels were not included in clinical studies of ZOMETA® in TIH