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Key Zometa (zoledronic acid) clinical trials ZOMETA is the current standard of care for the prevention of skeletal-related events (SREs)
 

Published Clinical Trials

Kohno N.,
Zoledronic Acid Significantly Reduces Skeletal Complications Compared With Placebo in Japanese Women With Bone Metastases From Breast Cancer: A Randomized, Placebo-Controlled Trial
Journal of Clinical Oncology (2005)

Rosen L., et al.
Long-Term Efficacy and Safety of Zoledronic Acid in the Treatment of Skeletal Metastases in Patients with Nonsmall Cell Lung Carcinoma and Other Solid Tumors A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial
Cancer (2004)

Saad F., et al.
Long-Term Efficacy of Zoledronic Acid for the Prevention of Skeletal Complications in Patients With Metastatic Hormone-Refractory Prostate Cancer
Journal of the National Cancer Institute (2004)

Lipton A., et al.
Zoledronic Acid Delays the Onset of Skeletal-Related Events and Progression of Skeletal Disease in Patients with Advanced Renal Cell Carcinoma
Cancer (2003)

Rosen L., et al.
Long-Term Efficacy and Safety of Zoledronic Acid Compared with Pamidronate Disodium in the Treatment of Skeletal Complications in Patients with Advanced Multiple Myeloma or Breast Carcinoma A Randomized, Double-Blind, Multicenter, Comparative Trial
Cancer (2003)

Rosen L., et al.
Zoledronic Acid Versus Placebo in the Treatment of Skeletal Metastases in Patients With Lung Cancer and Other Solid Tumors: A Phase III, Double-Blind, Randomized Trial—The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
Journal of Clinical Oncology (2003)

Saad F., et al.
A Randomized, Placebo-Controlled Trial of Zoledronic Acid in Patients With Hormone-Refractory Metastatic Prostate Carcinoma
Journal of the National Cancer Institute (2002)

Rosen L., et al.
Zoledronic Acid versus Pamidronate in the Treatment of Skeletal Metastases in Patients with Breast Cancer or Osteolytic Lesions of Multiple Myeloma: A Phase III Double-Blind, Comparative Trial
The Cancer Journal (2001)